tag:blogger.com,1999:blog-109934792012-01-26T05:19:10.167-08:00Christopher W. V. Hogue Ph.D. Biochemistry and Bioinformatics @cwvhogue.Christopher Hoguehttp://www.blogger.com/profile/17959173395982455577noreply@blogger.comBlogger121100tag:blogger.com,1999:blog-10993479.post-43997964864250535682012-01-26T05:14:00.000-08:002012-01-26T05:19:10.184-08:00

Author Steven Berlin Johnson has stated quite plainly that an idea is a network of neurons (1). These networks can today be crudely but dynamically visualized with advanced brain scanning. Within this network of neurons, transient connections bring together the fuzzy memories of designs we carry.  When we connect  existing designs together, complexity grows from simplicity. Humans encourage their

Christopher Hoguehttp://www.blogger.com/profile/17959173395982455577noreply@blogger.com0tag:blogger.com,1999:blog-10993479.post-57261276261143944132012-01-17T18:47:00.000-08:002012-01-17T19:06:10.537-08:00

In this series I write about human design, and show how human design processes that lead to mass produced items of complexity are similar to evolutionary processes in living systems. So far, I have shown only a few examples. In this essay I will explain a framework with which one can understand the human design process.  I start by describing the “agents” in human design, and a simple

Christopher Hoguehttp://www.blogger.com/profile/17959173395982455577noreply@blogger.com0tag:blogger.com,1999:blog-10993479.post-3472955454692260892012-01-09T21:48:00.000-08:002012-01-10T08:24:25.084-08:00

Glass bottle closures from corks to bottle caps are small things to which we do not give much thought. But their design and deployment over the last century elegantly illustrate the competitive, messy and often unpredictable process of human design in action. Let us start with the mechanical requirements for sealing glass bottles. The most demanding of these are sodas, sparkling wines and

Christopher Hoguehttp://www.blogger.com/profile/17959173395982455577noreply@blogger.comtag:blogger.com,1999:blog-10993479.post-5907358053959909022012-01-04T22:01:00.000-08:002012-01-04T22:02:10.292-08:00

This year I am starting a new blog series here in “BioImplement” with examples of human design and how they inform us, by analogy, about the origin of complexity by evolution. I will also plug our new Mechanobiology content resource (http://manual.blueprint.org) to be released  on Jan 15th at www.mechanobiology.info . Today’s posting is a preview of what you can expect to be reading here about

Christopher Hoguehttp://www.blogger.com/profile/17959173395982455577noreply@blogger.comtag:blogger.com,1999:blog-10993479.post-68247353377939805182009-02-01T23:05:00.000-08:002009-02-02T18:55:34.595-08:00

Recent news of the 2009 Canadian Budget and the "missing" Genome Canada funding has created a minor media frenzy. Several Ontario scientists, my colleagues, friends and mentors, are being paraded by the news organizations as examples of how Genome Canada has created international leadership in cancer genomics and biodiversity research. Good for them, but I also I feel badly for them, for I know

Christopher Hoguehttp://www.blogger.com/profile/17959173395982455577noreply@blogger.com0tag:blogger.com,1999:blog-10993479.post-67482392847374143492008-11-13T04:58:00.000-08:002008-11-13T05:03:19.414-08:00

After a year of being in Singapore, I finally posted a new website for my current research lab activities. http://www.blueprint.org. Take a look, you may be pleasantly surprised by the content.

Christopher Hoguehttp://www.blogger.com/profile/17959173395982455577noreply@blogger.com0tag:blogger.com,1999:blog-10993479.post-47861345366828564592008-06-18T17:35:00.000-07:002008-06-18T17:47:39.143-07:00

Have you Limited your Liability Today?The following disclaimer is posted for the benefit of my employer The National University of Singapore and to any other interested parties who are worried about liability. These parties should also note the extensive BLOGGER.COM terms of service.The BioImplement Disclaimer V2.0Opinions expressed on BioImplement are entirely those of the author, Dr.

Christopher Hoguehttp://www.blogger.com/profile/17959173395982455577noreply@blogger.com0tag:blogger.com,1999:blog-10993479.post-21863785207224698162008-06-17T01:10:00.000-07:002008-06-17T01:24:25.724-07:00

Like many other bloggers with good intentions, my blog has faded into oblivion. It seems "blogging" is a fad reserved for the interested few.As an update, I am currently an Associate Professor in the Department of Biological Science at the National University of Singapore. I am working on research projects involving both Bioinformatics and wet-laboratory protein and nucleic acid biochemistry

Christopher Hoguehttp://www.blogger.com/profile/17959173395982455577noreply@blogger.com0tag:blogger.com,1999:blog-10993479.post-1165595469718547272006-12-08T08:29:00.000-08:002006-12-08T08:49:13.636-08:00

It has been a long while since I posted last, and without summarizing events, I am no longer employed by Mount Sinai Hospital and the Blueprint Initiative is now, obsolete. My status-only position at the University of Toronto's Dept. of Biochemistry is dependent on my, now terminated, employment at MSH. So it appears like I am no longer a faculty member at Canada's largest University, and they

Christopher Hoguehttp://www.blogger.com/profile/17959173395982455577noreply@blogger.com0tag:blogger.com,1999:blog-10993479.post-1131569557417620772005-11-16T12:50:00.000-08:002005-11-16T15:04:43.986-08:00

Today, November 16 2005, it was announced that BIND curation activities have ceased, due to lack of public funding for the ongoing effort for the Blueprint Initiative in both Canada and Singapore. While it is difficult to provide public databases of the caliber of BIND without continued funding, I remain committed to public good research, open source software development and free data deposition,

Christopher Hoguehttp://www.blogger.com/profile/17959173395982455577noreply@blogger.com0tag:blogger.com,1999:blog-10993479.post-1109038617184916622005-05-30T06:08:00.000-07:002005-05-30T06:20:49.666-07:00

Have you Limited your Liability Today?The following disclaimer is posted for the benefit of my employer, Mount Sinai Hospital (MSH) in Toronto, and my primay academic institution, The University of Toronto (UofT) and to any other interested parties who are worried about liability. These parties should also note the extensive BLOGGER.COM terms of service which I read in its entirety (including the

Christopher Hoguehttp://www.blogger.com/profile/17959173395982455577noreply@blogger.com0tag:blogger.com,1999:blog-10993479.post-1109031603043811832005-02-21T16:19:00.000-08:002005-02-21T16:20:03.043-08:00

Watch This Space.

Christopher Hoguehttp://www.blogger.com/profile/17959173395982455577noreply@blogger.com0